HORDB

ID: hor001175
Uniprot ID: A8XJC3
Protein name: FLP-18
Gene name: flp-18
Organism: Caenorhabditis briggsae
Family: FMRFamide related peptide family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Caenorhabditis (genus), Peloderinae (subfamily), Rhabditidae (family), Rhabditoidea (superfamily), Rhabditomorpha (infraorder), Rhabditina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0006937 regulation of muscle contraction; GO:0007218 neuropeptide signaling pathway; GO:0030431 sleep
GO CC: GO:0005576 extracellular region

Sequence: DFDGAMPGVLRF
Length: 12
Propeptide: MQRWSGVIFITLCCLLREASAYTEPIYEIVEDDIPAEDIEVTRGNEKQDGRVFNKRDFDGAMPGVLRFGKRGGVWEKRESSVQKKEMPGVLRFGKRAYFDEKKSVPGVLRFGKRSYFDEKKSVPGVLRFGKRDVPMDKREIPGVLRFGKRDYTEEMFDKRSEVPGVLRFGKRDVPGVLRFGKRSDLEEHYAGVLLKKSVPGVLRFGRK
Signal peptide: MQRWSGVIFITLCCLLREASA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor001175_AF2.pdb

hor001175_ESM.pdb

Mass:	152091	Formula:	C60H89N15O17S
Absent amino acids:	CEHIKNQSTWY	Common amino acids:	DFG
pI:	4.11	Basic residues:	1
Polar residues:	2	Hydrophobic residues:	5
Hydrophobicity:	28.33	Boman Index:	-1140
Half-Life:	1.1 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	65
Instability Index:	5875.83	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 18760316
Title: Comparative Peptidomics of Caenorhabditis Elegans Versus C. Briggsae by LC-MALDI-TOF MS